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Home Cycling

How One Rider’s Mission Came Full Circle Through CAR T-Cell Therapy: Steve Mars’ Story

July 30, 2026
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How One Rider’s Mission Came Full Circle Through CAR T-Cell Therapy: Steve Mars’ Story


Most cancers has at all times hit too near residence for Steve. In 2008, Steve’s mom was identified with late-stage metastatic breast most cancers, and Steve quickly found that he had non-Hodgkins follicular lymphoma. His mom handed away just a few days after Steve began therapy.

“There I used to be getting chemo, my first infusion, and primarily, I felt like my mother was sending me her final little bit of life so I might transfer on,” Steve says.

And Steve did. He put his head down, pursued the therapy and ultimately reached remission. He remained cancer-free for nearly 17 years.  

Then, in 2020, Barb was identified with triple unfavorable breast most cancers.

“I went by way of therapy, and it’ll be 5 years for me on July twentieth,” Barb says. “However you get to a sure section in your life, and also you understand what’s vital, what comes into focus. This occurred to me throughout my most cancers journey. I feel Steve is there too, ?”

For Steve and Barb, household got here into focus. This has particularly rung true since Summer season 2025. Amidst coaching for Empire State Journey, Steve began to really feel off. There have been lumps in his neck, and he received unwell in a short time. It quickly turned obvious that Steve’s most cancers had returned. By means of all of it, his household and mates rallied round him.

The months that adopted blurred between chemotherapy and journeys to the ER. In December, Steve was declared in remission and rang the victory bell to represent the tip of his therapy. Solely 5 weeks later, he began displaying stroke-like behaviors, and scans revealed the most cancers had emerged in his mind. Throughout extra chemotherapy therapies, Steve was admitted to the ICU for issues from RSV. Although the weakened diseased cells responded to chemotherapy, a number of the extra cussed most cancers cells remained.

That’s when Steve’s care workforce determined to pivot to the therapy that Steve spent so a few years serving to to advance: CAR T-cell remedy. First, he needed to bear a number of rounds of radiation to bridge the gaps to CAR T-cell remedy. Then, a number of rounds of chemotherapy got to wipe out his present T cells and make room for the genetically engineered “tremendous” cells. Steve had his T cells eliminated, genetically modified in a lab to assault most cancers cells and reinfused.

The highway forward is lengthy, however Steve finds peace in figuring out that he has so many extra therapy choices immediately than he did 17 years in the past when CAR T-cell remedy wasn’t round.

“That is yr ten of my mission [to end cancer]. And one of many issues that actually stands out to me is unbelievable change that we’ve seen within the final ten years … SurVaxM, CAR T-cell remedy and different unbelievable advances,” Steve says. “I’m keen to do no matter it takes to make most cancers cease.”



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Tags: Breast CancercancerCancer researchcarCirclecycle to end cancerend cancerFullfundraise for a causefundraiserMarsmissionRidersStevestorysurvivor storiesTCellTherapyvictory bell
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